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Lewis sarett cortisone

2019-11-22 13:53

Oct 28, 2016  Lewis H. Sarett became quite famous in his own right. He was the first chemist to synthesize cortisone. It was a feat of remarkable complexity involving nearly 40 chemical steps from desoxycholic acid and was achieved during World War II as aDec 27, 1999 Dr. Lewis Hastings Sarett, 81, Leader in Cortisone Research. He was cited for his contributions to the chemical synthesis of various chemotherapeutic agents, including cortisone, used in the treatment of inflammatory, allergic and neoplastic diseases. The synthesis of cortisone was Dr. Sarett's first assignment at Merck, which he joined as a research scientist in 1942. lewis sarett cortisone

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Dr. Lewis Hastings Sarett, an organic chemist who received the National Medal of Science for his work with cortisone and other substances as the senior vice president for science and technology of Merck& Company, died on Nov. 29 at his home in Viola, Idaho. He was 81 and lived in Princeton and Akillman, N. J. , before he retired in 1982. The cause was advanced colitis, his family said.

Chemist Lewis Hastings Sarett prepared a synthetic version of the hormone cortisone, which was soon demonstrated as an effective treatment against rheumatoid arthritis. Born in Champaign, Illinois, Sarett received his B. S. from Northwestern University in 1939 and his Ph. D. from Princeton in 1942.

Aug 01, 2010 In 1942 a chemist from Merck and Company, Lewis Sarett, worked for 3 months in Kendall's laboratory and then returned to Merck with the goal of developing largescale synthetic methods for Compounds A and E. Yields of the individual steroids were low, with only between 85 and 500 mg of cortisone isolated per 100 lb of adrenal glands.

LEWIS H. SARETT WAS the first chemist to synthesize cortisone. It was a feat of remarkable complexity involving nearly 40 chemical steps from desoxycholic acid and was achieved during World War II as a chemist in the Merck Research Laboratories.

Lew Sarett and his group accomplished a total synthesis of cortisone, which he announced in 1952. Although it did not go into production, Sarett was very proud of that achievement, which the Annual Reports of the Chemical Society said was the best synthetic chemistry contribution of that year. Saretts cortisone achievements brought him acclaim

Lewis Sarett begins his oral history interview by telling of his early life in Wisconsin and Illinois, the influence of his father, and some of his experience in college and graduate school. He then turns to his first assignment at Merck, the synthesis of cortisone.

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Lewis Hastings Sarett (December 22, 1917 November 29, 1999) was an American organic chemist. While serving as a research scientist at Merck& Co. , Inc. , synthesized cortisone. Contents

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